The New Rani

She is played by Helena Bonham Carter.

The Regeneration
When Lucy Simmons and Katie O Mara's Rani are fighting in the TARDIS in The beaches of Mars, Lucy accidentally shoots Rani causing her to regenerate into her newer self. She says these iconic words: " Well then i heard of a revamp but this is just bizarre. I'm NEW AND FULL OF LIFE AND READY TO KILL A GOOD MAN." These words sparked rumors that River Song is Rani.

After
At the end of Innocent blood, River song gets a letter in the post with the signature:  Ainr Nda RTEMAS itch is anagram for rani and master. Its later found that the letter sent river to the libary and later her death. Meaning the Rani killed the doctor inside by killing River.

Appearances
The beaches of mars Innocent blood PROSE: Fight for life Prose: Life after Life TV: Light's end Tv: Tunnel vision Audio: The mark of Murder Tv: The horror beneath